The observed effects of Cx40 inhibition or deletion on individual platelets analysed by flow cytometry (fibrinogen binding and P-selectin exposure; Fig. 3a–h) point towards the importance of Cx40 ...

Platelets are small types of blood cells that prevent excessive bleeding. It’s possible to develop low or high platelet counts related to a number of health conditions. Platelets are one of the main ...

"Platelets are the smallest blood cells that work in clotting to heal cuts because they stick to the site of the injury," said Xia, a member of OMRF's Cardiovascular Biology Research Program. "This ...

Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of ...

Have you ever been in a classroom and wondered to yourself whether the information being presented could be wrong? During graduate school, I audited a medical school class in which the professor ...

Intravital microscopy image from the liver of a mouse model: a platelet (turquoise) adheres to the inflamed vessel wall (yellow dashed outline) and sheds a long, filamentous membrane extension—a ...

A team from Würzburg has fundamentally changed our understanding of platelet biology with a study published in Science. The researchers demonstrate that the surface protein integrin αIIbβ3 is not only ...