Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.

Professor Asaf Hellman and his research team at the Hebrew University-Hadassah Medical School have unveiled new findings in the realm of methylation-directed regulatory networks. Their study sheds ...

Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of ...

Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...

It's a common storytelling trope: the stubborn foe who is eventually revealed to be a much-needed friend. Biology has its own version. Cornell researchers have discovered that DNA packaging structures ...

Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...