A research team led by Professor Yuanliang ZHAI at the School of Biological Sciences, The University of Hong Kong (HKU) collaborating with Professor Ning GAO and Professor Qing LI from Peking ...
Before a cell divides, its DNA is replicated so that each daughter cell inherits the same genetic information. The two copies, known as "sister chromatids," are held together by a ring-shaped protein ...
Patients with this genetic disorder have a form of dwarfism — they are short in stature and have underdeveloped ears and ...
A new single-molecule flow-stretch assay enables real-time observation of DNA-protein interactions to identify the molecular ...
The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...
Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.
The human genome may have been sequenced, but we are still learning about how it works. One of the features of the genome scientists are still deciphering is epigenetics, which refers to the various ...
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A protein thought to play a supporting role in DNA replication actually facilitates the whole process
Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...
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