Researchers utilized non-targeted liquid chromatography-tandem mass spectrometry (LC-MS/MS) to analyze the serum metabolic ...

Stable isotope-labeled internal standards are widely used in laboratory-developed clinical mass spectrometry tests. An equal amount of these internal standards is added to all samples in a batch, ...

High-performance liquid chromatography (HPLC) or ultra-high-performance liquid chromatography (UHPLC) serves as the front end of the analysis, reducing sample complexity before mass detection.

Figure 1. A schematic representation of a lipid nanoparticle encapsulating mRNA. As this new form of biotechnology makes a leap of progress, so too do the analytical approaches supporting its ...

While each method has its pros and cons, a joint study found that LC-MS provides a clearer, more comprehensive picture of the ...

Biomarkers play an important role in drug development and help in the identification of disease-causing proteins found in blood, urine, body fluids, and tissue samples. The combination of liquid ...

LC separates the components of a mixture based on their affinity to a stationary or mobile phase and subsequently detects these components using ultraviolet light, fluorescence, or electrical ...