Must-win AFC North and NFC South showdowns? No. 1 seeds on the line? We have picks, predictions, stats and what's at stake for every Week 18 game.

The Week 18 NFL schedule and the regular season conclude on Sunday since there is no 'Monday Night Football' this week. It's the final opportunity to set NFL DFS lineups with a full player pool, and some of the big names available on the Week 18 'main slate' include Drake Maye,

The Las Vegas Raiders are close to securing the No. 1 overall pick in the 2026 NFL draft. All the Raiders have to do is lose for the 15th time this season on Sunday to sit atop the draft order. Four 3-13 teams are in the mix for No. 1 overall pick if the Raiders miraculously beat the Kansas City Chiefs.

The Tampa Bay Buccaneers are home this week for the season finale to take on the 8-8 Carolina Panthers for an NFC South clash to decide the division (sort of). If Carolina wins, they outright win the division. If Tampa Bay wins, they will hope the Saints can defeat the Falcons to claim the division crown.

The Buffalo Bills won't be AFC East champions this season, but they can still improve their seeding in the NFL playoffs if they beat the New York Jets and have results go their way elsewhere in Week 18.