Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...
A research team led by Purdue University's W. Andy Tao has discovered a new type of protein modification related to cellular ...
Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...
Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in general.
A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...
Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...
A Nature study identifies a previously unknown protein modification, O-2-hydroxyglutarylation, driven by the oncometabolite ...
Unlike bacteria or yeast, moss can produce large polypeptides of human collagen along with the post-translational modifications that make it stable and bioactive.
Paired Box 3 (PAX3) is a protein that plays a critical role in the formation of tissues and organs during embryonic ...
Neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, present a significant health challenge, affecting over 50 million people globally. One common feature of these diseases is the ...