Identification of variants influences treatment decisions. Inhibitors of the poly-ADP-ribose polymerase (PARP) system, a pathway for repairing single-stranded DNA breaks, are recommended for tumors ...
Phase 3 TALAPRO-3 results show that talazoparib plus enzalutamide significantly improves radiographic progression-free survival in HRR-mutated metastatic castration-sensitive prostate cancer, ...
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