Researchers show that small molecules that alter RNA structure have a greater functional impact than those that only bind. The findings offer a new framework for designing more effective RNA-targeting ...

An experimental RNA therapy from Avidity Biosciences has early clinical trial results showing it reduced by half the expression of a gene at the root of a rare, inherited form of muscular dystrophy ...

A protein called LENG8 traps defective RNA molecules inside the cell nucleus before they can reach the cytoplasm and disrupt normal cellular function, according to a study published in Molecular Cell ...

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

The field of RNA-targeted therapeutics is rapidly evolving, offering groundbreaking opportunities for the treatment of a wide array of diseases ...

A new study shows a single RNA injection may help repair heart damage after a heart attack, reducing scarring and improving ...

Contrary to historic understanding of RNA’s longevity in cells, some RNAs can persist in cells throughout the life of an organism. Lead authors, Martin Hetzer, PhD, president of the Institute of ...

A study of a bacteria commonly used in dairy fermentation revealed how organized RNA helixes, called riboswitches, can combine different signals to keep gene expression in check. Researchers from the ...

Biologists have discovered that disruptions in transfer RNA function can lead to the development of cleft lip and cleft palate. Cleft lip and cleft palate are among the most common birth defects, ...