The overall duration of a receptor–ligand complex will be influenced by both the rate of ligand association (k on) and the rate of binary complex dissociation (k off) 5, as discussed below. However, ...
When a drug molecule binds to its target protein, it stays bound for some time before eventually unbinding the target. The actual time how long a drug molecule resides bound to its target varies among ...
A new study helps to explain what defines how long a drug molecule stays bound to its target. A new study from the University of Eastern Finland and the University of Tübingen helps to explain what ...