Recent advances in optical physics have redefined the classical boundaries imposed by diffraction. Super-resolution imaging techniques, which once adhered strictly to the Rayleigh criterion, now ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Existing super-resolution techniques still face considerable challenges in complex deep tissue environments. For example, Stimulated Emission Depletion (STED) microscopy relies on a doughnut-shaped ...

Researchers have demonstrated that consumer-grade 3D printers and inexpensive materials can produce advanced optical components capable of super-resolution imaging. Each custom lens costs less than $1 ...

A research team drawn from collaborators across the USA has developed a super-resolution photoacoustic imaging method that ...

eDL-cSIM: An AI-driven super-resolution imaging method that captures high-quality live-cell dynamics in a single exposure, enhancing speed, resolution, and environmental robustness for advanced ...

A set of new imaging tools now allows researchers to see how specific fat molecules, called phospholipids, are distributed ...

Serine serves as a metabolic nexus in tumors, coordinating one-carbon metabolism, nucleotide synthesis, and redox regulation. In recent years, targeting the serine metabolic pathway, particularly the ...

Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

When analyzed with a grating, the amplified Raman signals provide extremely high-resolution spectra that surpass traditional instrumental limits by employing super-resolution correlation methods.

It has been over a decade since super-resolution microscopy was awarded the 2014 Nobel Prize in Chemistry, and after tremendous advancements over the years, it is on its way to becoming a standard ...