Overall picks to win: 8-8 in Week 17 (173-82-1 for the season) Picks to win with 1-5 confidence: 4-7 (103-64-1) Picks to win with 6-10 confidence: 4-1 (70-18) Overall to cover the spread: 9-6-1 (130-117-9) Cover-the-spread picks with 1-5 confidence: 8-4-1 (107-93-8) Cover-the-spread picks with 6-10 confidence: 1-2 (23-23-1)

Here are three things to know about the Indianapolis Colts vs. Houston Texans Week 18 game, plus a prediction.

Highlights from the Week 18 matchup between the Arizona Cardinals and Los Angeles Rams during the 2025 NFL season.

Each pick has a confidence level of 1-10, with 10 being the most confident. For more information on the pick methodology, check out the Week 1 edition of this series. Keep in mind that since the idea here is to make high-percentage plays,

Two playoff spots and the two No. 1 seeds will be decided on the NFL’s final weekend of the regular season, along with four division winners and other seeding issues.