Without a clear-cut favorite from the top seeds to the final wild-card teams, the playoffs figure to be as difficult to predict as all the surprises that led up to a fresh field of 14 teams. Here's breaking down our best bets to survive and advance in another round of picks and predictions against the spread: The 49ers ' offense will do its best to make up for an injury-riddled defense.

Pro Bowl left tackle Trent Williams and wide receiver Ricky Pearsall will both officially be questionable for the San Francisco 49ers for their wild-card playoff game against the Philadelphia Eagles o...

Saquon Barkley started off slow this season but picked up steam, averaging 100 rushing yards per game over the last four weeks.