The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 on a 53-37 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

The NFL wraps up the 2025-26 regular season this weekend as Week 18 will finalize the 2026 playoff bracket and the first 18 picks of the 2026 NFL Draft. We’ll see an assortment of teams resting players in preparation for the playoffs, as teams without a chance at a bye are looking to get ready for next weekend’s Wild Card round.

Nolan Bianchi, Richard Silva, John Niyo and Bob Wojnowski of The Detroit News offer their predictions for Week 18 of the NFL season.

However Sunday night, the 272nd and final game of the regular season, will have winner-take-all stakes as the archrival Pittsburgh Steelers and Baltimore Ravens vie for the AFC North title in the latest installment of their border way. The loser goes gets nothing.

Sam Farmer makes his picks and predictions for the final week of the NFL regular season, with the 49ers beat the Seahawks and the Steelers prevailing.

Florio’s pick: 49ers 27, Seahawks 24. Simms’s pick: Seahawks 28, 49ers 24. A meaningless game will have plenty of meaning, if Tampa wins on Saturday. Florio’s pick: Saints 23, Falcons 20. Simms’s pick: Falcons 24, Saints 17.

Los Angeles Rams vs. Arizona Cardinals picks, predictions, odds, win probabilities for NFL Week 18 Sunday game on Jan. 4. Who will win game today?

RotoBaller's Week 18 NFL DFS value plays, sleeper picks, and tournament stacks for daily fantasy football on FanDuel, DraftKings, and Yahoo. Win big in DFS with our expert research and advice.

Our PackersNews coverage team predicts the outcome of the Green Bay Packers Week 18 game against the Minnesota Vikings on Jan. 4.