Cancer researchers have long treated genetic chaos and epigenetic rewiring as separate engines of disease, two parallel ...
Zimislecel is an allogeneic stem cell-derived islet cell therapy that could eliminate the need for insulin in those who have ...
A research paper by scientists from Beijing Institute of Technology investigated the anti-tumor effect of millimeter waves ...
Jonas Salk quietly built the polio vaccine through rigorous, methodical work in Pittsburgh: treating patients, refinin ...
The capacity of an organism to regenerate depends on cell dedifferentiation followed by proliferation. Mammals, in general, have limited regenerative capacity. Now, a team of researchers at the Salk ...
Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...
It is well known that adding a mixture of four reprogramming molecules (Oct4, Sox2, Klf4 and c-Myc) also known as “Yamanaka factors” to cells can reset epigenetic marks to their original patterns.
A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...
Atomic defects in nanodiamonds enable both precise heating of lysosomes inside macrophages and nanoscale temperature ...
Cells of a multicellular organism are functionally heterogeneous owing to the differential expression of genes. Historically, differential gene expression had been thought to involve the genetic ...