The technology, called the Viral-Engineered RNA-based Activation System (VERAS), hijacks the virus's own replication ...

The replication of potentially harmful adenoviruses can be significantly reduced in human cells in cell culture by using the so-called CRISPR-Cas9 system ("gene scissors"). This method, which is used ...

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in ...

ELF3 axis enables luminal progenitor transformation in BRCA1-deficient breast cancer by reducing genomic instability and promoting progenitor identity.

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

This new resource aims to change that by providing a detailed framework for understanding how different cancers maintain their telomeres and where their weaknesses lie.

Scientists have uncovered a surprising viral shortcut that turns moving cells into delivery vehicles for infection. Instead ...

Most of an animal cell’s DNA is stored in its nucleus, packaged into chromosomes that help maintain order. But cancer cells often carry another type of DNA: molecules separate from the rest of the ...