Risk-bearing provider organizations rely on physicians to achieve cost savings. The literature on physician-mediated interventions to reduce costs is scant and provides little guidance on effective ...

Average current-mode control, as shown in Figure 1, is common in continuous-conduction-mode (CCM) power factor correction (PFC). It has two loops: a voltage loop that works as an outer loop and a ...

This 40sqm cabin, known as The Pod, is designed as a complete living system. Every function — sleeping, cooking, working — is integrated with precision. Instead of space, the design prioritizes ...

A new study in the American Journal of Preventive Medicine reports findings from a randomized controlled trial—the gold standard study design in health research—showing that promoting drinking water ...

The FDA is raising the bar for approval of CAR T-cell therapies in oncology. Under plans outlined by the FDA’s biologics chief Vinay Prasad, M.D., the agency will require developers of many CAR-Ts to ...

Abstract: Safety and data efficiency are important concerns in data-driven control, especially for nonlinear systems with unknown dynamics and subject to disturbances. In this work, we consider a ...

Recent randomized controlled trials (RCTs) in patients with prolonged disorders of consciousness (pDoC) have yielded limited success. Among them, only studies involving amantadine have provided Class ...

Background: Patients with intermediate-high risk pulmonary embolism (PE) have an elevated right-to-left-ventricular (RV/LV) diameter ratio and are at risk of early clinical decompensation and ...

What policies and programs can society implement to make a tangible, lasting impact on people’s lives? Social scientists have been trying to answer this question for decades by conducting randomized ...

Introduction Schizophrenia is a severe mental disorder. While some antipsychotic medications have demonstrated efficacy in treating positive symptoms, there is no widely recognized treatment for ...

Idiopathic normal-pressure hydrocephalus is a neurologic disorder characterized by impaired gait, balance, cognition, and bladder control in older adults. The disorder is treated with shunt surgery, ...

Malaria causes about 1/4 billion new cases of disease and about 600,000 deaths every year. 3/4 of the deaths are children under 5 years old. The July 23, 2025, NEJM has a free full text article ...